
Continuation of life starts from cells either those of the general body
or the sex cells (gametes).
Virchow (1821-1902) a proponent of cell theory is given the credit
for the phrase Omnis cellula de cellula, or cells arise from pre-existing
cells, indicates the importance of cell division in the creation of new cells.

In 1852 a German scientist, Robert Remak, published his
observations on cell division, based on his observations of embryos.
This was one of the first attempts to understand the mechanism of
cell division. He stated that binary fission of cells was the means of
reproduction of animal cells. What happens during cell division
could only be understood better when scientists came to know what
is present inside the nucleus of the cell.
In 1879 Walther Flemming (1843-1905) examined many kinds
of animal and plant cells and selected those that showed division.
He reported from his observations of such cells that there were
string like structures in the nucleus which split longitudinally during cell
division. He named such a process of division as mitosis (mitos- means
fine threads) as the dividing structures resembled threads. He made a
meticulous observation and made sketches and observed that there were a
sequence of events in the process of division. A decade later these thread
like structures were named as chromosomes (coloured bodies) as
repeatedly in efforts to see them scientists were trying to use dyes to
stain the nucleus and found that these structures were stained most often.
His most important discovery was chromosomes appear double in nature.
Wilhelm Roux (1850-1924) proposed that chromosomes carried a
different set of heritable elements and longitudinal splitting observed by
Flemming, ensured the equal division of these elements. Combined with
the rediscovery of Gregor Mendel's 1866 paper on heritable elements in
peas, these results highlighted the central role of the chromosomes in
carrying heritable material (or genetic material). In cell division the cell
divides into two halves with equal number of chromosomes which are
similar to parent cell and are diploid in nature.
But the chromosomes number always remained the same. Biologists.